As a human rights lawyer Charlotte has a particular interest in marginalized groups, children, women and people with disabilities. In 1999, she was appointed by the President of South Africa to the South African Human Rights Commission, and reappointed in October 2002. At the Commission she focussed on socio-economic rights, disability rights and child rights, and was responsible for two provinces Mpumalanga and Limpopo. She currently is on a leave from the Commission to be at the World Bank where she is the Disability Advisor to the East Asia and Pacific region and the South Asia region. Charlotte has worked with various UN agencies, has represented the National Human Rights Institutions at the UN during the process of developing a Convention for People with Disabilities, and serves on a number of community boards. She is currently the deputy Chairperson of the Council of the University of South Africa, has written widely on human rights issues and is committed to social justice.